That was the end of Ludo, but not of the Kressh bloodline. Ludo had at least one child, a son named Elcho, also called Kressh the Younger, who was safely hidden away on a remote planet. Elcho eventually attempted to get revenge on the Republic and the Jedi by assembling a ad hoc force of mercenaries and pirates to serve as a invasion force; however, he died from a ruptured stomach after heavily drinking before he could put it to use.
Another powerful descendant of Ludo, was the renowned alchemist Vodal Kressh. The Sith Lord lived in the reconstituted Sith Empire centuries before the Great Galactic War, until he rebelled against the Emperor and fled to the planet Athiss, planning to amass an army to attack the Sith Empire, although he died before executing his plan. Even after his death there, Vodal's followers and their descendants remained on Athiss protecting his tomb.
There were other descendants of Ludo who came to serve the Sith Emperor's reformed Empire, the most famous being the Emperor's apprentice Exal Kressh, who became disillusioned with the Emperor, and attempted to betray him. Before her betrayal, the Kressh name was considered one of the Empire's noblest, as its scions over the generations were thought great champions of the Sith cause. Exal tried to sabotage the Emperor's Children project, but failed and was killed.
Afterwards, the Emperor, in retaliation for her betrayal, declared that the very name of Kressh was an abomination and ordered all evidence of the family line throughout the Empire to be eliminated, with the Kressh family totally obliterated from the entire history and fabric of the Empire, in the hope that the relatives of his renegade apprentice would never again oppose him. Despite that order, the Kressh name and line continued to survive, and still produced rebellious Lords and scions well into the Empire's future.