A cruise missile was a high-powered missile propelled by a basic engine. The pirate Nym had these weapons loaded into his Havoc during the Occupation of Karthakk, as did Reti and Jinkins on their craft, the Zoomer and Freefall respectively.
Trade Federation cruisers also employed cruise missiles. Waves of these projectiles were launched at Nym's forces while assembling an Orbital Defense Cannon on Khons.